- July 18, 2014:
Scientists at the Salk Institute have identified a gene responsible for stopping the movement of cancer from the lungs to other parts of the body, indicating a new way to fight one of the world's deadliest cancers. Deviously, lung cancer cells can switch on and off molecular anchors allowing the cancer cells to traverse the body through the bloodstream and take up residence in new organs which is why it’s so invasive and has such a high mortality rate.
The newly discovered pathway, detailed today in Molecular Cell, may also help researchers understand and treat the spread of melanoma and cervical cancers.Full Story
- July 17, 2014:
Scientists are creating a biological pacemaker by injecting a gene into the hearts of sick pigs that changed ordinary cardiac cells into a special kind that induces a steady heartbeat.
The study is one step toward developing an alternative to electronic pacemakers that are implanted into 300,000 Americans a year. "There are people who desperately need a pacemaker but can't get one safely," said Dr. Eduardo Marban, director of the Cedars-Sinai Heart Institute in Los Angeles, who led the work. "This development heralds a new era of gene therapy" that one day might offer them an option. Full Story
- July 16, 2014:
One Injection of the protein FGF1 Stops Diabetes in Its Tracks for mice with diet-induced diabetes — the equivalent of type 2 diabetes in humans — for more than two days. The discovery by Salk scientists, published today in the journal Nature, could lead to a new generation of safer, more effective diabetes drugs.
"Controlling glucose is a dominant problem in our society," says Ronald M. Evans, director of Salk's Gene Expression Laboratory and corresponding author of the paper. "And the protein FGF1 offers a new method to control glucose in a powerful and unexpected way."Full Story
- July 8, 2014:
The first evidence for a shockless treatment for atrial fibrillation (AF) was presented Friday at Frontiers in CardioVascular Biology (FCVB) 2014 in Barcelona, Spain. The meeting was organized by the Council on Basic Cardiovascular Science of the European Society of Cardiology (ESC) in collaboration with 13 European cardiovascular science societies.
The researchers devised a method of shockless defibrillation by using optogenetics to genetically insert depolarizing ion channels into the heart that can be activated by light. Dr. Bingen said, “The theory was that we could just turn a light switch on and depolarize the entire myocardium without needing a shock.Full Story
- July 6, 2014:
The small intestine is not easy to examine but researchers at the University of Buffalo are developing a new imaging technique involving nanoparticles suspended in liquid to form "nanojuice" that patients would drink. "Conventional imaging methods show the organ and blockages, but “nanojuice” allows you to see how the small intestine operates in real time," said corresponding author Jonathan Lovell, PhD, UB assistant professor of biomedical engineering. "Better imaging will improve our understanding of irritable bowel syndrome, celiac disease, Crohn’s disease and other gastrointestinal illnesses allowing doctors to more effectively care for people suffering from them.Full Story